Fig. 2: Protective efficacy of DTMUV mRNA vaccine in SPF ducks.
From: An mRNA vaccine provides effective protection against Duck Tembusu Virus infection
A Experimental timeline depicting the prime-boost vaccination schedule and subsequent viral challenge. SPF ducks received primary immunization on Day 7 followed by a boost dose on Day 28. Serum samples were collected at indicated timepoints (red arrows) for antibody analysis. Virus challenge was performed on Day 49 with DTMUV strain JS804. B Kinetics of DTMUV-specific neutralizing antibody titers in duck sera following immunization. C Protection after DTMUV challenge in vaccinated and control ducks. Data points represent mean ± SEM (n = 5). Statistical analyses were performed using two-way ANOVA with Bonferroni’s multiple comparisons test and log-rank (Mantel-Cox) test. Statistical significance between vaccinated and control groups is indicated by asterisks (****P < 0.0001).
