Fig. 2: In vivo attenuation of the triple-deletion virus dBTF. | npj Vaccines

Fig. 2: In vivo attenuation of the triple-deletion virus dBTF.

From: A new attenuated and highly immunogenic orthopoxvirus vaccine protects against mpox in mice and macaques

Fig. 2: In vivo attenuation of the triple-deletion virus dBTF.

A The sizes of erythemas induced by intradermal inoculation of viruses on rabbit backs (n = 4). B, C The body weight changes, survival rates (n = 5 mice) (B) and viral loads in the tissues (n = 4 mice) (C) of BALB/c mice intranasally inoculated with 2.5 × 105 PFU of viruses. D, E The body weight changes, survival rates (n = 5 mice) (D) and viral loads in the tissues (n = 4 mice) (E) of BALB/c mice intranasally inoculated with 2.5 × 106 PFU of viruses.

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