Fig. 3: Reduced neurovirulence of the attenuated virus dBTF. | npj Vaccines

Fig. 3: Reduced neurovirulence of the attenuated virus dBTF.

From: A new attenuated and highly immunogenic orthopoxvirus vaccine protects against mpox in mice and macaques

Fig. 3: Reduced neurovirulence of the attenuated virus dBTF.

A–C The body weight changes (n = 5 mice) (A), survival rate (n = 5 mice) (B), and viral loads in the brains (n = 4 mice) (C) of BALB/c mice intracranially inoculated with 1 × 103 PFU of viruses. D–F The body weight changes (n = 5 mice) (D), survival rates (n = 5 mice) (E), and viral loads in the tissues (n = 4 mice) (F) of BALB/c nude mice intranasally inoculated with 2.5 × 105 PFU of viruses.

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