Fig. 2: Development and characterization of different 85A-NP, EC-NP and RT-NP. | npj Vaccines

Fig. 2: Development and characterization of different 85A-NP, EC-NP and RT-NP.

From: A novel nanoparticle vaccine displaying multistage tuberculosis antigens confers protection in mice infected with H37Rv

Fig. 2

a Size exclusion chromatography results (SEC) of 85A, EC and RT antigens, 85A-NP, EC-NP, RT-NP and naked NP on a Superdex200 increase 10/300GL column. b Dynamic light scattering (DLS) of 85A-NP, EC-NP and RT-NP and naked NP. c Characterization of 85A-NP, EC-NP, RT-NP and naked NP. d Negative-staining EM of 85A-NP, EC-NP, RT-NP and naked NP. The average measurement of diameter is indicated by the arrows (n = 3 individual measurements), and the negative-staining electron microscope image of all nanoparticles is presented with a scale bar of 200 nm.

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