Table 1 EU vaccines for adults tracker and landscape (last update April 2025)
From: Overview of vaccines for adults authorized, recommended, and implemented in the European Union
Pathogen | Pathogen type | Manufacturer | Brand name | Platform | (Most common) route of administration | Antigen | Adjuvant |
|---|---|---|---|---|---|---|---|
Avian influenza | Virus | CSL Seqirus | Zoonotic Influenza Vaccine Seqirus | Inactivated | Intramuscular | A/Astrakhan/3212/2020 (H5N8)-like strain (CBER-RG8A) (clade 2.3.4.4b) | MF59 |
Chikungunya | Virus | Bavarian Nordic | Vimkunya | Subunit (virus-like-particle) | Intramuscular | CHIKV capsid protein (C) and envelope proteins E1 and E2 derived from CHIKV Senegal strain 37997 | Alum-based |
Chikungunya | Virus | Valneva | Ixchiq | Live attenuated | Intramuscular | CHIKV Δ5nsP3 strain | None |
Dengue | Virus | Sanofi | Dengvaxia | Live attenuated | Intramuscular | Yellow Fever (YF) 17D backbone with DENV-1-4 | None |
Dengue | Virus | Takeda | Qdenga | Live attenuated | Intramuscular | DENV-2 backbone with DENV-1-4 | None |
Diphtheria, Tetanus (Td) | Bacteria | AJ Vaccines | diTeBooster | Subunit (toxoid) | Intramuscular | Tetanus toxoid, Diphtheria toxoid | Alum-based |
Diphtheria, Tetanus (Td) | Bacteria | Astro Pharma | Td-pur/DIFTETALL | Subunit (toxoid) | Intramuscular | Tetanus toxoid, Diphtheria toxoid | Alum-based |
Diphtheria, Tetanus (Td) | Bacteria | Sanofi | Tenivac/dT-reduct “Merieux” | Subunit (toxoid) | Intramuscular | Tetanus toxoid, Diphtheria toxoid | Alum-based |
Diphtheria, Tetanus, Pertussis (Tdap) | Bacteria | GSK | Boostrix | Subunit (toxoid) | Intramuscular | Diphtheria toxoid, Pertussis toxoid, and Tetanus toxoid | Alum-based |
Diphtheria, Tetanus, Pertussis (Tdap) | Bacteria | AJ Vaccines | diTekiBooster | Subunit (toxoid) | Intramuscular | Diphtheria toxoid, Pertussis toxoid, and Tetanus toxoid | Alum-based |
Diphtheria, Tetanus, Pertussis (Tdap) | Bacteria | Sanofi | Triaxis/Covaxis/Adacel | Subunit (toxoid) | Intramuscular | Diphtheria toxoid, Pertussis toxoid, and Tetanus toxoid | Alum-based |
Diphtheria, Tetanus, Pertussis, Polio (Tdap-IPV) | Bacteria/Virus | Sanofi | Adacel-Polio/Repevax | Inactivated/subunit (toxoid) | Intramuscular | Diphtheria toxoid, Pertussis toxoid, and Tetanus toxoid, Combined with Inactivated Poliomyelitis Vaccine (type 1-3) | Alum-based |
Diphtheria, Tetanus, Pertussis, Polio (Tdap-IPV) | Bacteria/Virus | GSK | Boostrix Polio | Inactivated/subunit (toxoid) | Intramuscular | Diphtheria toxoid, Pertussis toxoid, and Tetanus toxoid, Combined with Inactivated Poliomyelitis Vaccine (type 1-3) | Alum-based |
Diphtheria, Tetanus, Polio (Td-IPV) | Bacteria/Virus | Sanofi | Revaxis | Inactivated/subunit (toxoid) | Intramuscular | Diphtheria toxoid and Tetanus toxoid, Combined with Inactivated Poliomyelitis Vaccine (type 1-3) | Alum-based |
Haemophilus influenzae type b (Hib) | Bacteria | Sanofi | Act-HIB | Subunit (conjugate) | Intramuscular | Hib polysaccharide conjugated to tetanus toxoid | None |
Haemophilus influenzae type b (Hib) | Bacteria | GSK | Hiberix | Subunit (conjugate) | Intramuscular | Hib polysaccharide conjugated to tetanus toxoid | None |
Hepatitis A (HepA) | Virus | Sanofi | Avaxim | Inactivated | Intramuscular | HepA (GBM strain) | Alum-based |
Hepatitis A (HepA) | Virus | GSK | Havrix | Inactivated | Intramuscular | HepA (HM175 hepatitis A virus strain) | Alum-based |
Hepatitis A (HepA) | Virus | MSD | Vaqta Adult | Inactivated | Intramuscular | HepA (Strain CR:326F) | Alum-based |
Hepatitis A/B (HepA/B) | Virus | GSK | Twinrix Adult | Inactivated/subunit (recombinant protein) | Intramuscular | HepA inactivated, Hepatitis B surface antigen (HBsAg) | Alum-based |
Hepatitis B (HepB) | Virus | GSK | Engerix B | Subunit (recombinant protein) | Intramuscular | HepB surface antigen (HBsAg) | Alum-based |
Hepatitis B (HepB) | Virus | MSD | HBVaxPro | Subunit (recombinant protein) | Intramuscular | HepB surface antigen (HBsAg) | Alum-based |
Hepatitis B (HepB) | Virus | GSK | Fendrix | Subunit (recombinant protein) | Intramuscular | HepB surface antigen (HBsAg) | AS04C |
Hepatitis B (HepB) | Virus | Dynavax Technologies | Heplisav B | Subunit (recombinant protein) | Intramuscular | HepB surface antigen (HBsAg) | CpG 1018 (TLR9) |
Human papillomavirus (HPV) | Virus | MSD | Gardasil | Subunit (virus-like-particle) | Intramuscular | L1 - HPV 6-11-16-18 | Alum-based |
Human papillomavirus (HPV) | Virus | MSD | Gardasil9 | Subunit (virus-like-particle) | Intramuscular | L1 - HPV 6-11-16-18-31-33-45-52-58 | Alum-based |
Human papillomavirus (HPV) | Virus | GSK | Cervarix | Subunit (virus-like-particle) | Intramuscular | L1- HPV 16-18 | AS04 |
Japanese encephalitis (JE) | Virus | Valneva | Ixiaro | Inactivated | Intramuscular | JE virus (strain SA14-14-2) | Alum-based |
Measles, mumps, rubella (MMR) | Virus | MSD | M-M-R vax Pro | Live attenuated | Intramuscular | Measles virus - Enders’ Edmonston strain, Mumps virus - Jeryl Lynn [Level B] strain, Rubella virus - Wistar RA 27/3 strain | None |
Measles, mumps, rubella (MMR) | Virus | GSK | Priorix | Live attenuated | Intramuscular | Schwarz measles, the RIT 4385 mumps (derived from the Jeryl Lynn mumps strain) and the Wistar RA 27/3 rubella strains | None |
Measles, mumps, rubella, varicella (MMR-V) | Virus | GSK | Priorix tetra | Live attenuated | Intramuscular | Measles virus (Schwarz strain), mumps virus (RIT 4385 strain, derived from Jeryl Lynn strain), rubella virus (Wistar RA 27/3 strain), varicella virus (Oka strain) | None |
Measles, mumps, rubella, varicella (MMR-V) | Virus | MSD | ProQuad | Live attenuated | Intramuscular | Measles virus Enders’ Edmonston strain, Mumps virus Jeryl Lynn (Level B) strain, Rubella virus Wistar RA 27/3 strain, Varicella virus Oka/Merck strain | None |
Meningococcal ACWY | Bacteria | GSK | Menveo | Subunit (conjugate) | Intramuscular | Lyophilized meningococcal serogroup A (MenA) capsular polysaccharide conjugated to CRM197, capsular polysaccharide of serogroup C, W, and Y (MenCWY) conjugated to CRM197 | None |
Meningococcal ACWY | Bacteria | Sanofi | MenQuadfi | Subunit (conjugate) | Intramuscular | Neisseria meningitidis A,C, W,Y conjugated to tetanus toxoid carrier protein | None |
Meningococcal ACWY | Bacteria | Pfizer | Nimenrix | Subunit (conjugate) | Intramuscular | Neisseria meningitidis A,C, W-135,Y conjugated to tetanus toxoid carrier protein | None |
Meningococcal B | Bacteria | GSK | Bexsero | Subunit (recombinant protein) | Intramuscular | Neisseria meningitidis serogroup B surface proteins (NHBA, NadA, fHbp and PorA P1. 4) | Alum-based |
Meningococcal B | Bacteria | Pfizer | Trumenba | Subunit (recombinant protein) | Intramuscular | Neisseria meningitidis serogroup B fHbp (Recombinant lipidated fHbp (factor H binding protein) subfamily A-B | Alum-based |
Meningococcal C | Bacteria | Pfizer | Neisvac-C | Subunit (conjugate) | Intramuscular | Meningoccoal group C polysaccahride conjugated to tetanus toxoid carrier protein | Alum-based |
Mycobacterium tuberculosis (TB) | Bacteria | Biomed Lublin | BCG vaccine | Live attenuated | Intradermal | BCG (Moreau strain) | None |
Mycobacterium tuberculosis (TB) | Bacteria | BulBio-NCIPD | BCG vaccine | Live attenuated | Intradermal | BCG Russia seed strain (1950s) | None |
Mycobacterium tuberculosis (TB) | Bacteria | AJ Vaccines | BCG Vaccine “AJ Vaccines” | Live attenuated | Intradermal | Mycobacterium bovis BCG (Bacillus Calmette-Gué rin), Danish strain 1331 | None |
Mycobacterium tuberculosis (TB) | Bacteria | MSD | BCG TICE vaccine | Live attenuated | Intradermal | Strain developed at the University of Illinois from a strain originated at the Pasteur Institute. | None |
Polio | Virus | LG Chem Ltd | Eupolio | Inactivated | Intramuscular | Poliovirus types 1, 2 and 3 (Sabin strain) | None |
Polio | Virus | Sanofi | Imovax Polio | Inactivated | Intramuscular | Poliovirus Type 1 Mahoney, Type 2 MEF1, Type 3 Saukett | None |
Polio | Virus | Bilthoven Biologicals B.V | Poliomyelitis vaccine | Inactivated | Intramuscular | Poliovirus Type 1 Mahoney, Type 2 MEF1, Type 3 Saukett | None |
Rabies | Virus | Sanofi | Rabies Mérieux/ImoVax Rabies/Verorab | Inactivated | Intramuscular | Rabies virus (strain PM-1503-3M) | None |
Rabies | Virus | Bavarian Nordic | Rabipur | Inactivated | Intramuscular | Rabies virus (strain Flury LEP) | None |
Respiratory syncytial virus (RSV) | virus | GSK | Arexvy | Subunit (recombinant protein) | Intramuscular | F protein: RSVpreF (RSV A) | AS01E |
Respiratory syncytial virus (RSV) | virus | Moderna | mRESVIA (mRNA-1345) | Nucleic acid (mRNA) | Intramuscular | Single-stranded 5’ capped mRNA encoding the RSV-A glycoprotein F | None |
Respiratory syncytial virus (RSV) | virus | Pfizer | Abrysvo | Subunit (recombinant protein) | Intramuscular | F protein: RSVpreF (RSV A) and RSVpreF (RSV B) | None |
Salmonella Typhi | Bacteria | Emergent Biosolutions | Vivotif/Typhoral | Live attenuated | Oral | Salmonella typhi Ty21a | None |
Salmonella Typhi | Bacteria | Sanofi | Typhim Vi | Subunit (polysaccharide) | Intramuscular | Purified Vi polysaccharide from Salmonella Typhi (Ty2 strain) | None |
Seasonal Influenza | Virus | Fluart Innovative Vaccines | 3Fluart | Inactivated (egg-based) | Intramuscular | TIVs contain two A lineages (H1N1 and H3N2) and only one B lineage | Alum-based |
Seasonal Influenza | Virus | CSL Seqirus | Fluad/Chiromas | Inactivated (egg-based) | Intramuscular | TIVs contain two A lineages (H1N1 and H3N2) and only one B lineage | MF59 |
Seasonal Influenza | Virus | CSL Seqirus | Fluad Tetra/Quad /Quadrivalent | Inactivated (egg-based) | Intramuscular | QIVs contain two A lineages (H1N1 and H3N2) and two influenza B viruses | MF59 |
Seasonal Influenza | Virus | CSL Seqirus | Flucelvax Tetra/Quadrivalent/Quad | Inactivated (cell-based) | Intramuscular | QIVs contain two A lineages (H1N1 and H3N2) and two influenza B viruses | None |
Seasonal Influenza | Virus | CSL Seqirus | Afluria Quadrivalent/Quad/Tetra | Inactivated (egg-based) | Intramuscular | QIVs contain two A lineages (H1N1 and H3N2) and two influenza B viruses | None |
Seasonal Influenza | Virus | CSL Seqirus | Agrippal/Begripal/Fluazur/Sandovac/Agriflu/Chiroflu | Inactivated (egg-based) | Intramuscular | QIVs contain two A lineages (H1N1 and H3N2) and two influenza B viruses | None |
Seasonal Influenza | Virus | Sanofi | Efluelda | Inactivated (egg-based) | Intramuscular | QIVs contain two A lineages (H1N1 and H3N2) and two influenza B viruses (High-dose) | None |
Seasonal Influenza | Virus | GSK | Fluarix Tetra/Quadrivalent | Inactivated (egg-based) | Intramuscular | QIVs contain two A lineages (H1N1 and H3N2) and two influenza B viruses | None |
Seasonal Influenza | Virus | GSK | Flulaval Quadrivalent | Inactivated (egg-based) | Intramuscular | QIVs contain two A lineages (H1N1 and H3N2) and two influenza B viruses | None |
Seasonal Influenza | Virus | Abbott Biologicals B.V/Mylan | Influvac/Fluvaccinol/Grippe-Impfstoff STADA N/Vacciflu/Imuvac | Inactivated (egg-based) | Intramuscular | TIVs contain two A lineages (H1N1 and H3N2) and only one B lineage | None |
Seasonal Influenza | Virus | Abbott Biologicals B.V/Mylan | Influvac Tetra | Inactivated (egg-based) | Intramuscular | QIVs contain two A lineages (H1N1 and H3N2) and two influenza B viruses | None |
Seasonal Influenza | Virus | Sanofi | Vaxigrip | Inactivated (egg-based) | Intramuscular | TIVs contain two A lineages (H1N1 and H3N2) and only one B lineage | None |
Seasonal Influenza | Virus | Sanofi | Vaxigrip Tetra | Inactivated (egg-based) | Intramuscular | QIVs contain two A lineages (H1N1 and H3N2) and two influenza B viruses | None |
Seasonal Influenza | Virus | Sanofi | Supemtek Tetra | Subunit (recombinant protein) | Intramuscular | QIVs contain two A lineages (H1N1 and H3N2) and two influenza B viruses, high dose | None |
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) | Virus | Novavax | Nuvaxovid | Subunit (recombinant protein) | Intramuscular | Monovalent and Bivalent original and Omicron | Matrix-M |
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) | Virus | Pfizer/BioNTech | Comirnaty | Nucleic acid (mRNA) | Intramuscular | Monovalent and Bivalent original and Omicron - 30 μg encapsulated in LNPs | None |
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) | Virus | Moderna | Spikevax | Nucleic acid (mRNA) | Intramuscular | Monovalent and Bivalent original and Omicron (50 or 100 μg depending on dose) encapsulated in LNPs | None |
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) | Virus | Arcturus Therapeutics Europe B.V | Kostaive | Nucleic acid (self-amplyfing mRNA) | Intramuscular | Zapomeran, sa-mRNA,encapsulated in lipid nanoparticles | None |
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) | Virus | Hipra Human Health | Bimervax | Subunit (recombinant protein) | Intramuscular | Monovalent and bivalent, alfa, beta, omicron | SQBA |
Smallpox/ Mpox | Virus | Bavarian Nordic | Imvanex | Live attenuated (non-replicating) | Subcutaneous | Live, attenuated orthopoxvirus, Modified Vaccinia Ankara (MVA) | None |
Streptococcus pneumoniae | Bacteria | Pfizer | Prevenar 20 | Subunit (conjugate) | Intramuscular | Pneumococcal capsular polysaccharides 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, 22F, 23F, 33F, 8, 10A, 11A, 12F, 15B, | Alum-based |
Streptococcus pneumoniae | Bacteria | Pfizer | Prevenar 13 | Subunit (conjugate) | Intramuscular | Pneumococcal capsular polysaccharides 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, 23F | Alum-based |
Streptococcus pneumoniae | Bacteria | MSD | Vaxneuvance | Subunit (conjugate) | Intramuscular | Pneumococcal capsular polysaccharides 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, 22F, 23F, 33F | Alum-based |
Streptococcus pneumoniae | Bacteria | MSD | Pneumovax 23 | Subunit (polysaccharide) | Intramuscular | Polysaccharide antigen from 1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19F, 19A, 20, 22F, 23F, and 33F | None |
Streptococcus pneumoniae | Bacteria | MSD | Capvaxive (PCV21) | Subunit (conjugate) | Intramuscular | Polysaccharide antigen from 3, 6A, 7F, 8, 9N, 10A, 11A, 12F, 15A, 15B (de-O-acetylated prior to conjugation), 16F, 17F, 19A, 20A, 22F, 23A, 23B, 24F, 31, 33F, and 35B individually conjugated to CRM197 carrier protein. | None |
Tick-borne encephalitis (TBE) | Virus | Bavarian Nordic | Encepur | Inactivated | Intramuscular | TBE virus (strain K23) | Alum-based |
Tick-borne encephalitis (TBE) | Virus | Pfizer | FSME-Immun/Ticovac | Inactivated | Intramuscular | TBE virus (strain Neudö rfl) | Alum-based |
Varicella-zoster virus (VZV) - Herpes Zoster | Virus | GSK | Shingrix | Subunit (recombinant protein) | Intramuscular | Varicella Zoster Virus glycoprotein E antigen | AS01B |
Varicella-zoster virus (VZV) - Varicella | Virus | GSK | Varilrix | Live attenuated | Intramuscular | VZV strain Oka | None |
Varicella-zoster virus (VZV) - Varicella | Virus | MSD | Varivax | Live attenuated | Intramuscular | VZV strain Oka/Merck | None |
Vibrio cholerae O1 | Bacteria | Valneva | Dukoral | Inactivated/subunit (toxoid) | Oral | Inactivated Vibrio cholerae O1 (classical Inaba, El Tor Inaba, Ogawa) and Recombinant cholera toxin B subunit | None |
Vibrio cholerae O1 | Bacteria | Emergent BioSolutions | Vaxchora | Live attenuated | Oral | Vibrio cholerae live, attenuated strain CVD 103-HgR | None |
Yellow Fever (YF) | Virus | Sanofi | Stamaril | Live attenuated | Subcutaneous | YF virus 17D-204 strain | None |
Zaire ebolavirus | Virus | MSD | Ervebo | Viral vector | Intramuscular | Recombinant Vesicular Stomatitis Virus (rVSV) strain Indiana with a deletion of the VSV envelope glycoprotein (G) replaced with the Zaire Ebola Virus (ZEBOV) Kikwit 1995 strain surface glycoprotein (GP) | None |
Zaire ebolavirus | Virus | Janssen-Cilag International NV | Zabdeno/Mvabea | Viral vector | Intramuscular | Modified Vaccinia Ankara Bavarian Nordic Virus encoding the Zaire ebolavirus (EBOV) Mayinga variant glycoprotein (GP), Sudan ebolavirus Gulu variant GP, Taï Forest ebolavirus nucleoprotein, Marburg marburgvirus Musoke variant GP | None |
