Table. 1 Virus shedding in piglets post-challenge

From: A self-amplifying mRNA vaccine expressing PRV gD induces robust immunity against virulent mutants

Group

Number of animals with nasal shedding

Duration (days)

PRV saRNA gD-50 μg

3/3

5–7

PRV saRNA gD-5 μg

3/3

6

PRV saRNA gD-5 μg-Twice

3/3

4–6

PRV LA 2017

3/3

4–7

PRV LA-A-Twice

3/3

4–5

saRNA NC-50 μg-Twice

3/3

Dead or 10