Fig. 7: Quantification of the mAb proportion in sera from vaccinated mice and hamsters. | npj Vaccines

Fig. 7: Quantification of the mAb proportion in sera from vaccinated mice and hamsters.

From: Antigenic landscape of Nipah virus attachment glycoprotein analysis reveals a protective immunodominant epitope across species

Fig. 7

A–D ELISA showing the binding of NiV sGH (A, C) or NiV GH-ferritin (B, D) vaccinated sera to the immobilized NiVM G head domain protein in the presence of 10 μg/mL of mAbs from group 1 (S1E2 and LN1D1), group 2 (S2B10), group 3 (LN3A12 and LN3D3), group 4 (LN3E2 and LN3D3) and group 5 (HENV-32). The binding of the sera in the presence of an isotype control mAb T3D9 (anti-SFTSV mAb, unpublished) was used as a control, and the OD450 (absorbance at 450 nm) value was defined as 100%. Each graph represents the mean and SD from one experiment and is representive of two independent experiments performed in duplicate.

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