Fig. 6: CD8+ T cell cytokine responses in PBMCs at week 26. | npj Vaccines

Fig. 6: CD8+ T cell cytokine responses in PBMCs at week 26.

From: ALFQ adjuvanted HIV-1 envelope protein vaccination elicits durable functional antibody and cellular responses in nonhuman primates

Fig. 6

A–D The percentage of HIV-1 Env-specific CD8+ T cells secreting A IL-2, B IFN-γ, C TNF-α, and D IFN-γ and TNF-α are presented as mean ±  SEM. Each individual NHP is represented as a symbol (N = 7/group). A representative flow plot is shown on the right. E Boolean gating was applied to identify polyfunctional CD8+ T cells. Pie chart and the analysis and statistical significance between the groups was performed as described above. *p < 0.01 and **p < 0.003. The gating strategy and the flow panels are shown in Fig. S5C and Table S9, respectively.

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