Table 1 Immunodominant epitopes detected at day 35 post-infection

From: Multi-antigen DNA vaccine targeting non-structural proteins confers robust T Cell-mediated protection against Zika virus

Protein

Peptide pool

Peptide number

Sequence position (a.a.)

Peptide

Peptide length

CTL/Th T cell targets

NS1

P3

68

202–216

SEKNDTWRLKRAHLI

15

Th

69

205–219

NDTWRLKRAHLIEMK

15

P4

87

259–273

RTQMKGPWHSEELEI

15

CTL

88

262–276

MKGPWHSEELEIRFE

15

89

265–279

PWHSEELEIRFEECP

15

NS3

P3

76

298–312

RGYISTRVEMGEAAA

15

NS4

P1

27

183–200

DLRPASAWAIYAALTTFI

18

P2

33

225–242

GVLFGMGKGMPFYAWDFG

18

34

232–249

KGMPFYAWDFGVPLLMIG

18

Env

P1

20

58–72

SYCYEASISDMASDS

15

  1. Bolded amino acid residues represent the overlapping sequence shared between consecutive peptides.