Table 1 Leading SARS-CoV-2 vaccine candidates supported by Operation Warp Speed in the United States

From: Development of vaccines and antivirals for combating viral pandemics

Vaccine

Technology platform

Developers

Development status and clinical trial number

mRNA-1273 (ref. 29)

mRNA

Moderna Therapeutics and NIAID

Phase 3

NCT04470427

BNT162b2 (ref. 30)

mRNA

BioNTech RNA Pharmaceuticals and Pfizer

Phase 3

NCT04368728

AZD1222 (ref. 33)

Adenovirus vaccine

University of Oxford and AstraZeneca

Phase 3

NCT04516746

Ad26.COV2-S

Adenovirus vaccine

Johnson & Johnson

Phase 3

NCT04505722

–

Vesicular stomatitis virus- and measles-based

Merck Sharp and Dohme Corp.

Phase ½

NCT04498247