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CANCER IMMUNOTHERAPY

Filmed over with CAR-T cells

Nature Biomedical Engineering volume 4, pages 142–143 (2020)Cite this article

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Locally delivering therapeutic T cells into solid tumours in mice via thin nitinol films loaded with the cells lengthens the animals’ survival.

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Fig. 1: Delivery strategies for adoptive T-cell therapy.

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Acknowledgements

The authors are grateful for support from the National Cancer Institute (grant nos. U01CA214369 and U54CA244726) and the U.S. Food and Drug Administration (grant no. R01 FD006589).

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Authors and Affiliations

  1. John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA

    Kwasi Adu-Berchie & David J. Mooney

  2. The Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA

    Kwasi Adu-Berchie & David J. Mooney

Authors
  1. Kwasi Adu-Berchie
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  2. David J. Mooney
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Correspondence to David J. Mooney.

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Adu-Berchie, K., Mooney, D.J. Filmed over with CAR-T cells. Nat Biomed Eng 4, 142–143 (2020). https://doi.org/10.1038/s41551-020-0517-x

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