Extended Data Fig. 2: Kaem and Rhap induce expression of a broad spectrum of autophagy/mitophagy proteins. | Nature Biomedical Engineering

Extended Data Fig. 2: Kaem and Rhap induce expression of a broad spectrum of autophagy/mitophagy proteins.

From: Amelioration of Alzheimer’s disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow

Extended Data Fig. 2: Kaem and Rhap induce expression of a broad spectrum of autophagy/mitophagy proteins.

a, A representative set of western blot images for designated proteins upon Veh., Kaem (20, 50, 100 μM) or Rhap (20, 50, 100 μM) administration for 24 h. Arrow head in the right panel pointed to ‘FUNDC1’, with bands upper and lower were likely unknown or non-specific bands. b, c, Semi-quantification of a from three biological replicates with data shown in mean ± S.E.M. One-way ANOVA followed by Šidák’s multiple comparisons test was used for data analysis, with *p < 0.05, **p < 0.01, ***p < 0.001. Original western blot gels for (a) were included in Source Data Fig. 1.

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