Extended Data Fig. 3: Kinesin-2 knockout tumors exhibit differentiation defects.

a, Representative photographs of whole, unfixed growths retrieved from immunodeficient animals at the same time point. Growths are sliced through their centers to reveal the internal surface. b, A second set of tumors, photographed intact after retrieval from the animals. c-e, Quantification of tissue subtypes within teratomas as a fraction of total area (mean ± s.e.m., n ≥ 5 independent biological replicates per condition from a total of 14 distinct cell lines). f, Ratio of area occupied by SOX2+ cells in TUJ1+ patches of teratoma sections (mean ± s.e.m., n ≥ 4 independent biological replicates per condition from a total of 6 distinct cell lines; *, p = 0.0391).