Extended Data Fig. 2: SGLT1 aids the uptake of PGNPs into cells.
a, Representative confocal images showing SGLT1-mediated endocytosis of PGNPs in SGLT1-expressing HEK293T cells. PNPs or PGNPs (red), SGLT1 (green), and nucleus (blue). Scale bars, 5 μm (left panel), 1 μm (middle and right panels). b, Quantification of the percentage of PNPs or PGNPs co-localized with SGLT1 during the internalization in confocal images. n = 3. All values are expressed as mean ± s.e.m. Statistical significance was determined using two-tailed Student’s t-test in b. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. a and b are representative of two independent experiments.
