Extended Data Fig. 8: Cell-type dependencies for Spearman’s ρ between MENTR mutation effects and βQTL. | Nature Biomedical Engineering

Extended Data Fig. 8: Cell-type dependencies for Spearman’s ρ between MENTR mutation effects and βQTL.

From: Prediction of the cell-type-specific transcription of non-coding RNAs from genome sequences via machine learning

Extended Data Fig. 8: Cell-type dependencies for Spearman’s ρ between MENTR mutation effects and βQTL.The alternative text for this image may have been generated using AI.

Y-axis, Spearman’s ρ between MENTR mutation effects and effect size from the QTL studies (βQTL; see Fig. 4) for each model (each dot represented one of the FANTOM5 347 sample ontologies and LCL and the dashed line indicated the ρ value for LCL); x-axis and color key, transcriptome correlation between with LCL CAGE transcriptome and each of FANTOM5 347 CAGE transcriptome. We excluded variants with 0 mutation effect from this analysis. P-values were calculated by two-sided Spearman’s rank correlation test. p < 2.2×10−16 indicated that the p-value was lower than the default machine epsilon value (2.2×10−16).

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