Extended Data Fig. 4: Additional echocardiography results showing that iECM infusions mitigate negative LV remodelling in a pig acute MI model.
a, Representative M-mode echocardiographic images showing that iECM mitigates negative LV remodelling. Yellow arrows represent LV diastolic dimension, red arrows represent wall thickness, and white arrows represent wall thinning. b-g, LV diastolic dimension (LVDd, #p = 0.08), LV systolic dimension (LVDs), and fractional shortening (FS) over time (b,d,f) and changes from post-MI to 8 weeks post-MI (c, e (*p = 0.03), g (*p = 0.047)). h, Diagram demonstrating how infarct angle was measured. N = 10 all groups. Data are mean ± SEM. All data are biological replicates and were evaluated with a two tailed unpaired t-test.
