Extended Data Fig. 5: Data summary and analysis in the human study.

Flow diagram summarizing the human subjects and eyes included and excluded in the analysis. Eyes included in the analysis were grouped into three groups (more characteristics are provided in Supplementary Table 1). Group 1: Emmetropia or low myopia (3 D ≤ SE< −6 D) with no pathological conditions, 69 eyes from 42 subjects (23 female) with a mean age of 41.29 years, a mean SE of −1.74 D, and a mean AL of 24.44 mm. Group 2 : High myopia (≤ −6D) with no pathological conditions, 16 eyes from 9 subjects (8 female) with a mean age of 39.20 years, a mean SE of −7.72 D, and a mean AL of 26.88 mm. Group 3 : Pathologic myopia with staphyloma, 15 eyes from 9 subjects (6 female) with a mean age of 58.22 years and a mean AL of 29.05 mm. SE, Spherical equivalent refractive error. AL, Axial length.