Extended Data Fig. 5: Blood glucose and time to the lowest blood glucose at day 60 and 180 post-implantation in three-month diabetic mice. | Nature Biomedical Engineering

Extended Data Fig. 5: Blood glucose and time to the lowest blood glucose at day 60 and 180 post-implantation in three-month diabetic mice.

From: An injectable and biodegradable zwitterionic gel for extending the longevity and performance of insulin infusion catheters

Extended Data Fig. 5

Mice received insulin administration (4 IU/kg) through the lumen of the completely implanted catheter in treated and untreated groups and mice receiving syringe-based SC insulin injection at the same dosage were used as control (n = 6 biologically independent animals in each group, mean ± s.d.). A one-way ANOVA with Tukey multi-comparison was used for statistical analysis at day 60. A two-tailed t-test analysis was used for statistical analysis at day 180. For the untreated group at day 180 post-implantation, no insulin administration through the lumen of the implanted catheter only can be performed due to the occlusion of the untreated catheter.

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