Extended Data Fig. 1: Blood glucose and time to the lowest blood glucose at day 60 and 180 post-implantation in non-diabetic C57BL/6 mice. | Nature Biomedical Engineering

Extended Data Fig. 1: Blood glucose and time to the lowest blood glucose at day 60 and 180 post-implantation in non-diabetic C57BL/6 mice.

From: An injectable and biodegradable zwitterionic gel for extending the longevity and performance of insulin infusion catheters

Extended Data Fig. 1

Mice received insulin administration (2 IU/kg) through the lumen of the completely implanted catheter in treated and untreated groups and mice receiving syringe-based SC insulin injection at the same dosage were used as control (n = 6 biologically independent animals in each group, mean ± s.d.). A one-way ANOVA with Tukey multi-comparison was used for statistical analysis. For the untreated group at day 180 post-implantation, insulin administration through the lumen of the implanted catheter only can be performed in 2 of 6 mice due to the occlusion of the untreated catheter, and the valid blood glucose data are presented as mean (n = 2 biologically independent animals).

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