Extended Data Fig. 1: Longer homology arms increase integration with both HMEJ or HR. | Nature Biomedical Engineering

Extended Data Fig. 1: Longer homology arms increase integration with both HMEJ or HR.

From: Cas9-induced targeted integration of large DNA payloads in primary human T cells via homology-mediated end-joining DNA repair

Extended Data Fig. 1: Longer homology arms increase integration with both HMEJ or HR.

Percentage of cells expressing GFP following electroporation with Cas9 mRNA, gRNAs, and HMEJ templates with the indicated homology arm lengths. Statistical analyses were done using Two-way ANOVA (n = 3–6 independent biological donors) (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001).

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