Extended Data Fig. 4: Microglial staining in bPAC-expressing tissue. | Nature Biomedical Engineering

Extended Data Fig. 4: Microglial staining in bPAC-expressing tissue.

From: Imaging bioluminescence by detecting localized haemodynamic contrast from photosensitized vasculature

Extended Data Fig. 4

Comparison of bPAC expression profile (top) with distribution of the microglial marker Iba1 (middle) and overlay (bottom), showing absence of clear microglial activation in bPAC-rich areas in a representative BLUsH-treated brain hemisphere. Panels at right represent enlargements of the dashed areas in the panels at left. Areas 1 and 2 were chosen to be regions with and without substantial bPAC expression, respectively. Scale bars = 1 mm (left) or 500 µm (right).

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