Extended Data Fig. 3: mRNA quantification of transgenes in HEKhNORM2 and HEKhNORM3 by qPCR.
From: Nitroglycerin-responsive gene switch for the on-demand production of therapeutic proteins

(a) mRNA levels of sGCα, sGCβ, PKG1, and ALDH2 relative to those in WT non-engineered HEK-293 cells. (b) mRNA levels of sGCα, sGCβ, PKG1, ALDH2, NLuc, and GLP-1 following DETA NONOate (100 µM) treatment for 24 h. Values are shown relative to corresponding untreated cells. Data are presented as means ± s.d., n = 3. Source data are provided as a Source Data file.