Extended Data Fig. 6: Alive liver sections of mouse indicate tension in the center of ‘portal to portal’ direction. | Nature Biomedical Engineering

Extended Data Fig. 6: Alive liver sections of mouse indicate tension in the center of ‘portal to portal’ direction.

From: Tension-induced directional migration of hepatic stellate cells potentially coordinates liver fibrosis progression

Extended Data Fig. 6: Alive liver sections of mouse indicate tension in the center of ‘portal to portal’ direction.

a, The method to cut alive liver sections of a mouse and induce incisions. b, The shape change after loading an incision in the alive liver section. Scale bar, 200 μm. c, The stacked incision borders. d, The ratio of the width to the height of the incision. The experiment in b was repeated 3 times independently with similar results. Data in d (n= 3 biological replicates) are mean ± s.d. Statistical analysis in (d) was performed with the matched nonparametric Friedman test because the aspect ratio data were measured as a matched series from each individual sample. Exact P values are labeled. The video is Supplementary Video 5. a was created with BioRender.com.

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