Extended Data Fig. 10: Migration tracks of quiescent and activated HSCs on collagen loaded with different strain.

a, Migration tracks of quiescent HSCs. b, Migration tracks of activated HSCs. θ, the average migration angel. The average migration angel of a cell that migrates randomly is close to 45∘, whereas the average migration angel of a cell that migrates ideally along the strain direction is 90∘. How migration speed and average migration angel are calculated from time-lapse videos is explained in Supplementary Fig. 12.