Extended Data Fig. 5: CD45 cells decrease stepwise from non-DSD to DSD to ASD.
A, Representative images of immunohistochemistry stains for CD45 (brown) with nuclear counterstain (purple) in non-DSD, DSD, and ASD LF. B, Qualitative schematic demonstrating the observation that CD45 cells, when present, seemed to cluster together in regions of abnormal ECM. C, The most CD45 cells were seen in non-DSD samples (n = 3), fewer were seen in DSD samples (n = 3), and significantly fewest were seen in ASD samples (n = 3, p = 0.0254 from non-DSD, p = 0.0196 from DSD). Quantitative data are shown as mean ± sem, all tests are two-sided, unpaired t-tests.
