Table 1 Demographic information
From: Self-powered rapid antigen-specific T-cell response assay for Mycobacterium tuberculosis infections
TB status at enrollmenta | M.tb infection (N = 106) | Non-M.tb control (N = 61) | |
|---|---|---|---|
Median (IQR) or n (%) | Median (IQR) or n (%) | ||
Demographics | |||
Age (years) | 52.9 (13–88) | 47.7 (15–80) | |
Female sex (%) | 48 (45.3%) | 28 (46%) | |
HIV positive | 18 (17%) | 6 (9.9%) | |
Current or new anti-TB therapy | 19 (18%) | 2 (3.3%) | |
BCG history | 21 (19.9%) | 11 (18.1%) | |
TB features | |||
Cough | <2 weeks | 2 (1.9%) | 0 (0%) |
≥2 weeks | 14 (13.3%) | 2 (3.3%) | |
Recurrent or persistent fevers | <2 weeks | 2 (1.9%) | 2 (3.3%) |
≥2 weeks | 10 (9.5%) | 1 (1.7%) | |
Unexplained weight loss | ≤5% body weight loss | 10 (9.5%) | 2 (3.3%) |
>5% body weight loss | 4 (3.8%) | 0 (0%) | |
Drenching night sweats | <2 weeks | 9 (8.5%) | 1 (1.7%) |
≥2 weeks | 2 (1.9%) | 2 (3.3%) | |
Loss of appetite | <2 weeks | 2 (1.9%) | 2 (3.3%) |
≥2 weeks | 8 (7.6%) | 1 (1.7%) | |
Chest X-ray consistent with TB | 14 (13.3%) | 2 (3.3%) | |
Positive culture | 35 (33.1%) | 0 (0%) | |
Positive smear | 15 (14.2%) | 0 (0%) | |
Positive Xpert | 29 (27.4%) | 0 (0%) | |
Positive QFT/IGRA | 40 (37.8%) | 0 (0%) | |
Positive T-SPOT.TB (ESAT-6/CFP-10) | 48 (45.3%) | 0 (0%) | |
Positive ASTRA (4-1BB/OX-40) | 92 (86.8%) | 0 (0%) | |
