Extended Data Fig. 4: Culture within the IC-LOC does not induce substantial immune cell activation. | Nature Biomedical Engineering

Extended Data Fig. 4: Culture within the IC-LOC does not induce substantial immune cell activation.

From: An immune-competent lung-on-a-chip for modelling the human severe influenza infection response

Extended Data Fig. 4: Culture within the IC-LOC does not induce substantial immune cell activation.The alternative text for this image may have been generated using AI.

(a) Flow cytometry analysis of activation markers on CD3 + T and (b) CD56 + NK cell populations from PBMCs pre- and post- culture within the device, designated D0 PBMCs and IC-LOC, -H1N1, respectively. N = 5 samples, with two IC-LOC devices from the same immune cell donor pooled per sample for the IC-LOC samples. Statistical significance determined via two-tailed unpaired t-test, with p-values shown on graph and error bars showing S.E.M.

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