Extended Data Fig. 6: Tumour-associated antigen (TAA) screening in patient samples.
From: Lung tumouroids as a testing platform for precision CAR T cell therapy
a, Histoscore (H-score) heatmap for patients 9, 12, 17, and 18 across all screened TAAs: ErbB2/HER2neu (HER2), Mesothelin (MSLN), Mucin-1 (MUC1), programmed death-ligand 1 (PD-L1), hepatocyte growth factor receptor (cMET), carcinoembryonic antigen (CEA), and anaplastic lymphoma kinase (ALK) in healthy tissue (HT), healthy organoids (HO), tumour tissue (TT), or TOs (TO). b, Representative whole-slide IHC scan of HER2 staining in TO18, illustrating intra-organoid heterogeneity in marker expression. Scale bar, 100 μm.
