Fig. 6: Quantitative results of prediction of biomarkers/mutations using pathologists’ assigned grade. | Nature Biomedical Engineering

Fig. 6: Quantitative results of prediction of biomarkers/mutations using pathologists’ assigned grade.

From: Confounding factors and biases abound when predicting molecular biomarkers from histological images

Fig. 6: Quantitative results of prediction of biomarkers/mutations using pathologists’ assigned grade.The alternative text for this image may have been generated using AI.

The plots illustrate the AUROC achieved by a support vector machine classifier trained to predict a biomarker/gene mutation from one-hot encoded histological grades. Bar heights represent mean AUROC values, whereas error bars indicate the 95% confidence (two-sided, using Student’s t-distribution) calculated across 100 class-stratified bootstrap sampling runs. Bar labels are colour-coded, with yellow denoting biomarkers and green denoting mutations.

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