Extended Data Fig. 1: Methods for internal protein labeling using short peptide tags. | Nature Chemistry

Extended Data Fig. 1: Methods for internal protein labeling using short peptide tags.

From: Lysine acylation using conjugating enzymes for site-specific modification and ubiquitination of recombinant proteins

Extended Data Fig. 1: Methods for internal protein labeling using short peptide tags.The alternative text for this image may have been generated using AI.

Existing chemical (a) and chemoenzymatic methods (b) are summarized, together with the LACE method (c). Recognition sequence, as well as advantages and disadvantages of each method are listed. Parts of reagents and metabolites that can be altered to incorporate functional moieties are highlighted in red or shown as a red sphere.

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