Table 1 Precatalyst applicability for the direct C(sp2)–H bond arylation of directing-group arenes using (pseudeo)halide electrophiles under mild reaction conditions

From: An air- and moisture-stable ruthenium precatalyst for diverse reactivity

  1. aProcess-relevant conditions: 3 (3.5 mol%), 4-iodoanisole (1.05 equiv.), K2CO3 (3.0 equiv.), TBAOAc (30 mol%), DMC (0.5 M), 50 °C, 22 h.
  2. bYields determined by 1H NMR spectroscopy using an internal standard.
  3. c3 (20 mol%), 144 h.
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