Table 2 Optimization of the 1,2-alkoxy-hydroxylation of alkenes using alkoxy sulfonium salts

From: Activation of alcohols as sulfonium salts in the photocatalytic hetero-difunctionalization of alkenes

  1. General reaction conditions involved 1a (0.1 mmol), 3a (0.2 mmol), PC1 (0.1 mol%), Na2HPO4 (0.5 equiv.) and H2O (2.0 equiv.) dissolved in acetone (0.1 M) under irradiation by blue light-emitting diodes (LEDs; λmax centred at 456 nm) at –78 °C for 3 h. Yields were determined by 1H NMR spectroscopy using mesitylene as an internal standard. Isolated yields are reported in parentheses. DMF, N,N-dimethylformamide; NR, no reaction; tBu, tert-butyl.
Back to article page