Extended Data Fig. 1: Gram-scale preparation and synthetic transformation of stereogenic-at-P(V) compounds.

a, Gram-scale preparations. b, Transformation of SPOs (A) into diverse chiral phosphine ligands and catalysts. See general procedure VIII/X in Supplementary Information 7.2. *The product E13 was recrystallized once from a DCM/n-hexane mixture, affording optically pure compound in >99% ee with 86% yield.