Fig. 3: Environmentally induced epigenetic changes are transmitted to offspring regardless of genotype.
From: Epigenetic plasticity enables copepods to cope with ocean acidification
a, Circos plot showing Paracyclopina nana genome-wide DNA methylation profile (Supplementary Methods). b, Epigenetic variants associated with multigenerational resilience are independent of genetic variants. Genes with higher methylation in the offspring than in the parents are indicated in red, whereas blue indicates the opposite. The epigenetic inheritance factor (along the y axis) is contrasted with genotypic factors (along the x axis). The Pearson correlation coefficients (r) show that intergenerational epigenetic variation correlates weakly with adaptive genotype factors (0 < |r| < 0.2). mCG denotes a methylation at CpG sites. vsF0N indicates DMRs normalized to the F0N group. Δmeth denotes F1M–F0M and F2M–F1M, respectively.
