Extended Data Fig. 6: Relationship between mood drift and depression risk.
From: A highly replicable decline in mood during rest and simple tasks
Relationship between mood drift and depression risk. (a) Mood ratings over time of online participants at risk of depression (defined as MFQ>12 or CES-D>16) vs. those not at risk for the 768 participants with at least 6 minutes of resting mood data (error bars are SEM). The dotted line represents the mean initial rating (mean of cohort means). (b) We fitted simple regressions of time versus mood within each individual and determined significance of the time term with Benjamini-Hochberg false-discovery rate correction (2-sided α = 0.5, p<0.05) to better understand the relationship between depression risk and the change in mood over time. Depression risk is operationalised as score on the CES-D or MFQ divided by the threshold for depression risk on each measure (16 and 12 respectively). The line is a linear best fit, and the patch shows the 95% confidence interval of this fit. (c) Proportion of individuals with or without risk of depression (that is, depression risk >1 or <1) with positive (significantly greater than zero), non-significant (no evidence of a significant difference from zero), and negative (significantly less than 0) slopes of mood over time. 13 more individuals at risk of depression have a positive slope than the 35 expected based on the rates in individuals not at risk of depression, χ2(1,N=886)=14.57, p<0.001 (2-sided Pearson’s chi-squared statistic with no correction for multiple comparisons).
