Fig. 3: Cognitive matching of brain activity with canonical meta-analytic patterns is diminished under anaesthesia and restored upon recovery.
a, At each point in time, the cognitive matching score was computed as the best spatial correlation between brain activity and 123 Neurosynth meta-analytic maps. For each participant, an overall index of the quality of cognitive matching was then obtained by averaging the cognitive matching scores across the entire scan duration within each condition. b, The y axis indicates the mean across time of the cognitive matching score (n = 15 human volunteers). In the box plots, the central lines indicate median values, the bounds of the boxes indicate the 25th and 75th percentiles, the whiskers indicate 1.5× the interquartile range and extreme values are shown as individual circles. P values were obtained from repeated-measures t-tests (two sided) and false discovery rate corrected for multiple comparisons. Significance values for comparisons with the awake data are shown in black and those for comparisons versus the recovery data are shown in grey. See Supplementary Data 1 for full statistical reporting. Source data are provided. Avg, average; supp, suppression.
