Fig. 2: Higher theta power in the amygdala for CS− than for CS+ trials during extinction.
From: Representational dynamics during extinction of fear memories in the human brain
a, Amygdala 1–12 Hz power. During acquisition (left), no significant differences in low-frequency power were observed between CS+ and CS− trials. Bottom row: result of the contrast between the two conditions. Top and middle rows: levels of Z-scored power for each condition. During extinction (right), oscillatory power was significantly higher for CS− trials in a late time period of cue acquisition, that is, from 1.18 to 1.75 s in the 3–10 Hz frequency range. Negative T values depicted in blue reflect higher theta power for CS− items. b, T maps of the CS++ vs CS+− (top), CS++ vs CS−− (middle) and CS+− vs CS−− (bottom) contrasts. c, Top: CS+ vs CS− contrast in the frequency spectrum between 1 and 100 Hz. Bottom: average theta power in the cluster observed in a, bottom right, and c, top, for all CS types during the phases of acquisition and extinction. In a–c, two-sided paired t-tests were applied at each time–frequency bin (N = 32). Significant regions surviving correction for multiple comparisons using cluster-based permutation statistics are outlined in black in the time–frequency maps.
