Extended Data Fig. 5: Design of inducible lysyl oxidase expression in vivo using a TetOFF system in the background of MMTV-PyMT model. | Nature Materials

Extended Data Fig. 5: Design of inducible lysyl oxidase expression in vivo using a TetOFF system in the background of MMTV-PyMT model.

From: Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression

Extended Data Fig. 5

a, PCR results and sequence of PCR primers of N- and C-terminal ends to confirm TetO_mLox transgene incorporation. b, Diagram of inducible TetOFF system. TetO_mLox transgene is reversibly turned off or on in the presence or absence of doxycycline, respectively.

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