Extended Data Fig. 10: Piezo1 modulate NC cell spreading ex vivo.
From: Cell clusters softening triggers collective cell migration in vivo
(a–d) ex vivo results for the behaviour of Control, Piezo1-MO, and Piezo1-MO + hypoacetylated NC cells and clusters when migrating on a stiff permissive substrate; conditions as indicated in the figure. (a–c) Cell tracks depicting individual cell trajectories; (d) Rg2 ex vivo calculations showing collective spreading under the indicated conditions, line represents mean, and shadow SD. a–c, representative examples of at least 3 independent experiments. Related to Supplementary Movie 3.
