Lipid nanoparticles formulated with ionizable lipids inspired by brain-targeting small molecules facilitate the delivery of mRNA past the blood–brain barrier and into the brain.
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Han, E.L., Safford, H.C. & Mitchell, M.J. Designer lipids for delivering mRNA to the brain. Nat. Mater. 24, 1518–1519 (2025). https://doi.org/10.1038/s41563-025-02184-z
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DOI: https://doi.org/10.1038/s41563-025-02184-z
