Extended Data Fig. 6: Bioprinted hiPSC-derived cortical brain organoids exhibit matrix-dependent phenotypes and rosette organization.
From: Stress-relaxing granular bioprinting materials enable complex and uniform organoid self-organization
a. Live images of human iPSC-derived cortical organoids from three different donors (methods) bioprinted into arrays using AMG support baths. Scale bar = 1 mm. b. Cortical organoids bioprinted in MAGIC matrices show sprouting (arrow) and neuroepithelial budding (arrowheads). Scale bars = 1 mm (left) and 500 µm (right). c, d. 20 µm maximum intensity projections of bioprinted cortical organoids stained for (c) cortical identity and (d) neuronal differentiation. Scale bars = 50 µm.
