Extended Data Fig. 2: B6.Sst1SStinggt/gt partially rescues the enhance susceptibility of B6.Sst1S mice to Mtb.
From: Type I interferon-driven susceptibility to Mycobacterium tuberculosis is mediated by IL-1Ra
Mice were infected with Mtb and measured for lung bacterial burdens at day 25 (a) or survival (b). a, combined results of 2 experiments. Sample size n (B6, B6.Sst1S, B6.Sst1SStinggt/gt) = 11, 11, 12 (a); 11, 11, 11 (b). All animals except 5 of the B6 were bred in-house (a) and all except B6 were bred in-house (b). Center and error bars show mean and SEM. Analyzed with two-ended Mann–Whitney test (a) or two-ended Log-rank test (b). *P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001.
