Extended Data Fig. 4: Similarity of key ORFs to Lokiarchaeon genomes.

Each point represents a separate ORF detected in either the metagenomes (filled circles) or metatranscriptomes (white circles) that had a predicted protein in a Lokiarchaeon genome as its top hit in DIAMOND searches, which are displayed in the metabolic reconstruction in Fig. 3 in the main text. The abbreviations in Fig. 3 are shown at the top of the plot, the full names appear at the bottom of the plot.