Extended Data Fig. 5: Mice infected with ΔuxaC C. rodentium have only a mild increase in inflammation. | Nature Microbiology

Extended Data Fig. 5: Mice infected with ΔuxaC C. rodentium have only a mild increase in inflammation.

From: Diet-derived galacturonic acid regulates virulence and intestinal colonization in enterohaemorrhagic Escherichia coli and Citrobacter rodentium

Extended Data Fig. 5: Mice infected with ΔuxaC C. rodentium have only a mild increase in inflammation.

C3H/HeJ mice under non-infected conditions as well as at post-infection day 8 with WT or the ΔexuR, ΔuxaC and ΔexuRΔuxaC mutants. a, Haematoxylin-eosin-stained cecal patch tissues of C3H/HeJ mice. Representative images from two independent experiments, scale bars = 100 µm. b, Blinded histopathology scores of non-infected mice or infected with WT (n = 4) or the ΔexuR (n = 4), ΔuxaC (n = 4), and ΔexuRΔuxaC (n = 4) C. rodentium (n, number of biological replicates; results are representative of two independent experiments). The mean and P value for two-sided one-way ANOVA statistical analysis.

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