Extended Data Fig. 7: Correlates between the fitness profiles in amoebae and phylogenetic distances of individual Legionella species.

a, Pairwise comparisons define no correlation between the fitness profiles of 12 Legionella species (Fig. 5) and their phylogenetic relatedness. b, Pairwise comparisons between members of the same phenotypic group (Group I, II, III and IV as defined in Fig. 5) show strong positive correlations (blue) with the exception of L. dumoffii (Ld) and other Group I members (red). c, The fitness profile of L. dumoffii negatively correlates with that of all members of Group I, II and IV species (left panel) and is due to the decreased fitness of L. dumoffii in H. vermiformis relative to A. castellanii and N. gruberi (right panel). Plots are based on the phylogenetic distances and percent L. pneumophila intracellular growth reported in Fig. 5.