Extended Data Fig. 3: Single particle cryo-EM analysis of R2M2S1 bound to 44bp DNA. | Nature Microbiology

Extended Data Fig. 3: Single particle cryo-EM analysis of R2M2S1 bound to 44bp DNA.

From: Structural insights into assembly, operation and inhibition of a type I restriction–modification system

Extended Data Fig. 3

a, Representative cryo-EM micrograph of R2M2S1-DNA (44 bp). Experiments were performed two times independently with similar results. b, Representative reference-free 2D-class averages. Experiments were performed two times independently with similar results. c, The gold standard Fourier shell correlation (FSC) curve of final density map. d, Angular distribution of particles included in the final 3D reconstruction. e, Cryo-EM density map of R1M2S1-DNARAS (44 bp) colored on the basis of the local resolution. f, Data-processing workflow for R2M2S1-DNA (44 bp).

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