Extended Data Fig. 4: HIV-1 particles retained at the NPC over extended period upon Nup62 dimerization. | Nature Microbiology

Extended Data Fig. 4: HIV-1 particles retained at the NPC over extended period upon Nup62 dimerization.

From: Nuclear pore blockade reveals that HIV-1 completes reverse transcription and uncoating in the nucleus

Extended Data Fig. 4

HeLa cells expressing Nup62DG synchronously infected with Gag-Integrase-Ruby (GIR) labeled HIV-1 particles. 1 hour following synchronized infection, cells were treated with homodimerizing drug (HD) and imaged every 4 minutes for 1 hour. Snapshot of a GIR labeled virus particle (boxed region) at the indicated times during acquisition is shown. Similar pattern observed across 5 independent experiments.

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