Extended Data Fig. 8: D1122A and H171Y particle fractionation and scTCID50 measurements.
From: The shape of pleomorphic virions determines resistance to cell-entry pressure
a and b, Particle-length distributions derived from the electron micrographs as shown in Fig. 1a. Length data were normalized such that the total area under the bars is equal to 1 for all of the plots. The dotted vertical lines mark 0.25 µm length cutoff, and the percentage of particles longer than 0.25 µm is indicated above. Insets: the mean particle length for the entire population (black bar), or the subset of the population longer than 0.25 µm (grey bar). c and d, Sample D1122A (c) and H171Y (d) cell-death data plotted in Fig. 5c–e. The no-inhibitor baseline values (shown on all plots) were used in Fig. 5c or as values from which to calculate the infectivity shifts in the presence of M-Fab in Fig. 5d,e.
