Extended Data Fig. 8: Measurement of anti-SARS-CoV-2 Immunoglobulin levels and neutralization activity. | Nature Microbiology

Extended Data Fig. 8: Measurement of anti-SARS-CoV-2 Immunoglobulin levels and neutralization activity.

From: Microbial signatures in the lower airways of mechanically ventilated COVID-19 patients associated with poor clinical outcome

Extended Data Fig. 8

Levels of anti-SARS-CoV-2 Spike (a) and anti-SARS-CoV-2 receptor binding domain (RBD, b) antibodies in from 20 non-SARS-CoV-2 infected smoker controls and 142 severely ill COVID-19 intubated patients. Note that the signals for different isotypes cannot be compared because they are detected with different reagents. c, Comparisons of anti-SARS-CoV-2 RBD antibody levels in 142 BAL samples across subjects in different clinical outcome groups (*= Two-sided Mann–Whitney U p < 0.05). d, Neutralizing activity in BAL samples across subjects in different clinical outcome groups.

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