Extended Data Fig. 6: Patients with overproduction of Bacteroides vulgatus proteases have increased endoscopic and histological severity. | Nature Microbiology

Extended Data Fig. 6: Patients with overproduction of Bacteroides vulgatus proteases have increased endoscopic and histological severity.

From: Multi-omics analyses of the ulcerative colitis gut microbiome link Bacteroides vulgatus proteases with disease severity

Extended Data Fig. 6

a, Bacteroides protease production corresponds to increased endoscopic severity. The disease activity of overproducers, underproducers, and other patients are individually plotted over boxplots. Two-tailed, t-test p-values are displayed above the boxplots. Sample sizes include n = 16, 14 and 71 for overproducers, underproducers and others respectively. Boxplots are defined by the median, quartiles and 1.5x inter-quartile range. b, Bacteroides protease production corresponds to a patient population with a decreased proportion of patients in histological remission. Each UC patient sample was categorized by Bacteroides vulgatus protease production category and the percent of patients in histological remission is shown in a bargraph with the number of samples in each category displayed above each bar. Histological remission is defined here as Geboes Grade 3 = 0.

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